Preheat oven to 450 degrees F. Mix together seasonings in a dish. Rinse roast and pat outside with paper towels.
Coat outside, bottom, top, sides well with dry rub so it is well coated. Set inside a baking dish with a rack underneath or a waded up piece of foil so it isn't sitting directly on the bottom.
Bake at 450 for 15 minutes, then lower temp to 325 degrees F and bake until center reaches 135 degrees F for medium rare perfectly tender center. For a 2.1 lb. piece this took 60 minutes for us.
Remove and let it rest for 15 minutes before slicing.